99% high quality assay Docetaxel API powder

Brand Name: SGONEK

Price: $90 -$95/Gram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Food Grade, Medicine Grade

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Docetaxel Cas No.:  125354-16-7
Molecular Formula:  C45H55NO15 Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

99% high quality assay Docetaxel API powder

Product name: Docetaxel

Active ingredient: Docetaxel

CAS NO.: 114977-28-5

Specification: 99%

Molecular formula: C43H53NO14

Molecular Weight: 807.8792

Characters: white powder

Solubility: Soluble in DMSO at 200 mg/mL; soluble in ethanol at 100 mg/mL; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.

 

Docetaxel is one of the taxane type drugs that were originally developed from the yew tree. Docetaxel is a man made drug that was first made from yew tree needles. It is also known by its brand name, Taxotere. It works by stopping thecancer cells from separating into 2 new cells, so it blocks the growth of cancer.

A semi-synthetic, second-generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and cell death. This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Docetaxel has been studied for use as a radiation-sensitizing agent.


Item

  Specification

  Result

  Method

Product Information

Product name

docetaxel 

   

Part of the Plant

tree

Conform

/

Country of Origin

China

Conform

/

Organoleptic Data

Appearance

Fine powder

Conform

NLS-QCS-1008

Color

white Powder

Conform

GB/T 5492-2008

Odor& Taste

Characteristic

Conform

GB/T 5492-2008

Process Data

Solvent(s) Used

Water and ethyl alcohol

Conform

/

Extract ration

99%

Conform

 

Content

docetaxel ≥99%

99%

 

Drying Method

Spray drying

Conform

/

Excipient

Maltodextrin 

Conform

/

Physical Characteristics

Particle Size (80 mesh)

98.0%pass 80mesh

Conform

GB/T 5507-2008

Moisture

<5.0%

2.8%

GB/T 14769-1993

Ash Content

<4.0%

1.4%

AOAC 942.05, 18th

Solvent Residue

Eur. Pharm

Conform

NLS-QCS-1007

Heavy Metals

Total Heavy Metals

<10 ppm

Conform

USP <231>, method II

Arsenic

<1.0 ppm

Conform

AOAC 986.15, 18th

Lead

<1.0 ppm

Conform

AOAC 986.15, 18th

Mercury

<0.5 ppm

Conform

AOAC 971.21, 18th

Pesticide Residue

666

<0.2ppm

Conform

GB/T5009.19-1996

DDT

<0.2ppm

Conform

GB/T5009.19-1996

Microbiology

Total Plate Count

<1,000cfu/g

17cfu/g

AOAC 990.12, 18th

Total Yeast & Mold

<100cfu/g

3cfu/g

FDA (BAM) Chapter 18, 8th Ed.

E. Coli

Negative

Negative

AOAC 997.11, 18th

Salmonella

Negative

Negative

FDA (BAM) Chapter 5, 8th Ed.

 


1. Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer.

2. Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma.



Docetaxel is approved to be used alone or with other drugs to treat:

Breast cancer that is locally advanced or has metastasized (spread to other parts of the body) and has not gotten better with other chemotherapy. It is also used to treat breast cancer that is node-positive and can be removed bysurgery.Gastric (stomach) cancer that is advanced. It is used in patients who have not been treated with chemotherapy for advanced disease.Non-small cell lung cancer in certain patients whose cancer is locally advanced or has metastasized.Prostate cancer that has metastasized in men whose cancer is hormone-refractory (does not respond tohormone treatment).Squamous cell carcinoma of the head and neck that is locally advanced.

Docetaxel is also being studied in the treatment of other types of cancer.



Contact Us


Name:
E-mail:
Message:
 
上一篇:Medical Grade High Purity Powder Cas 154229-18-2 Abiraterone 下一篇:High Quality Poly-L-aspartic Acid 99% CAS No. 25608-40-6 Pol
  • Home
  • Product Category
  • Tel
  • About Us