Name: Dutasteride

Synonyms : (5alpha,17beta)-N-{2,5-Bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide

Molecular Formula : C27H30F6N2O2

Molecular Weight : 528.53
CAS:164656-23-9

Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate". In those who are being regularly screened 5-alpha-reductase inhibitor(finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases. 

Benign prostatic hyperplasia

Physicians use finasteride for the treatment of BPH, informally known as an enlarged prostate. The FDA-approved dose is 5 mg once a day. Six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment.  If the drug is discontinued, any therapeutic benefits reverse within about –8 months. Finasteride may improve the symptoms associated with BPH such as  difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow.
 

Male pattern baldness

Finasteride is used to treat male pattern hair loss (androgenetic alopecia) in men only. Treatment provides about 30% improvement in hair loss after six months of treatment,  and effectiveness only persists as long as the drug is taken.
 

Off-label uses

Finasteride is sometimes used in hormone replacement therapy for male-to-female transsexuals in combination with a form of estrogen due to its antiandrogen properties. However, little clinical research of finasteride use for this purpose has been conducted and  evidence of efficacy is limited.

Treatment of swollen Prostate

Male pattern hair loss

Seborrheic hair loss

Inherited hair loss