Pharmaceutical raw material Etoricoxib CAS: 202409-33-4

Brand Name: SGONEK

Price: $1250 -$1500/Kilogram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Etoricoxib Cas No.:  202409-33-4
Molecular Formula:  C18H15ClN2O2S Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

Pharmaceutical raw material Etoricoxib CAS: 202409-33-4


Item Name
Etoricoxib
CAS NO.
202409-33-4
Apparence
White Powder
package
Aluminum Bag;Drums
Purity
99%
Advantage
OEM;ODM
Warranty
2 Years If Keep It Well
Certificate
GMP/ISO9001
Payment
                        Trade Assurance;L/C;T/T;Western Union

Etoricoxib works by blocking the effect of a natural chemical called cyclo-oxygenase-2 (COX-2) enzyme. This enzyme helps to make other chemicals, called prostaglandins, in the body. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX-2 enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Anti-inflammatory painkillers like etoricoxib are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Etoricoxib eases pain and swelling (inflammation) in conditions like osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, and it may also be used for short periods of time in gout.



Item

Standard

Result

Appearance

White crystalline powder odorless, bitter taste 

Conforms 

IR Absorption

Consist with the spectra obtained with Cimetidine CRS. 

Conforms

UV Absorption

Should conform 

Conforms

Heavy metal

≤10ppm

<10ppm

Residue on ignition

≤0.2%

0.02%

Related substances 

Single impurity≤0.2%

0.15%

Total impurity≤1.0%

0.47%

Loss on drying 

≤0.5%

0.06%

Organic volatile impurities (ethanol) (loss on drying)

≤0.5%

0.06%

Assay (calculated with reference on dried substance)

98.0-100.0%

99.0%



Etoricoxib is indicated for the treatment of rheumatoid arthritis, psoriatic arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain, and gout.

 


Item

Standard

Result

Appearance

White crystalline powder odorless, bitter taste 

Conforms 

IR Absorption

Consist with the spectra obtained with Cimetidine CRS. 

Conforms

UV Absorption

Should conform 

Conforms

Heavy metal

≤10ppm

<10ppm

Residue on ignition

≤0.2%

0.02%

Related substances 

Single impurity≤0.2%

0.15%

Total impurity≤1.0%

0.47%

Loss on drying 

≤0.5%

0.06%

Organic volatile impurities (ethanol) (loss on drying)

≤0.5%

0.06%

Assay (calculated with reference on dried substance)

98.0-100.0%

99.0%


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