Pharmaceutcial Grade Raw Material Powder Flumazenil

Brand Name: SGONEK

Price: $100 -$150/Gram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Food Grade Pharmaceutical Grade

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Flumazenil Cas No.:  78755-81-4
Molecular Formula:  C15H14FN3O3 Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

Pharmaceutcial Grade Raw Material Powder Flumazenil

 

Product Name  Flumazenil
CAS No.  75755-81-4
Purity  99%
Appearance  White Powder
Molecular Formula  C15H14FN3O3
EINECS No.  616-650-9

Description: 

Flumazenil is an antagonist to allosteric binding on the GABAA receptor. Administration of Flumazenil has been shown to reverse many of the physiological effects associated with  and their modification of the GABAA system.

 


Items Specifications Results
Description White or almost white, crystalline powder Complies
Solubility Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in methanol. Complies
MP 198℃ to 202 ℃ 199.0℃~201.0℃
Appearance of solution Solution S in clear (2.2.1) and not more intensely colored than reference solution BY7 (2.2.2,method II) Complies
Dimethylformamide    diethyl acetal ≤ 1% Complies
Related Substances
Impurity B ≤0.2% 0.01%
Any other impurity ≤0.1% 0.01%
Total ≤0.2% 0.02%
Loss on drying ≤0.5% 0.16%
Residual Solvents
Chloroform ≤0.006% Complies
DMF ≤0.088% Complies
Sulphated ash ≤0.1% 0.03%
Assay 98.0%~102.0%

100.00%

 


1. Flumazenil is of benefit in patients who become excessively drowsy after ben zodia zepines are used for either diagnostic or therapeutic procedures.

2. It has been used as an antidote in the treatment of ben zodia zepine overdoses It reverses the effects of ben zodia zepines by competitive inhibition at the ben zodia zepine binding site on the GABAA receptor. There are many complications that must be taken into consideration when used in theacute care setting.

3. It has also been used in hepatic encephalopathy, though results have been mixed




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