China Factory Supply Pharmaceutical Intermediates CAS 137862

Brand Name: SGONEK

Price: $275 -$300/Kilogram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Medicine Grade, Valsartan

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Valsartan Cas No.:  137862-53-4
Molecular Formula:  C24H29N5O3 Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

China Factory Supply Pharmaceutical Intermediates CAS 137862

 

Name:

Valsartan
Grade:  Pharmaceutical Grade
MF: C24H29N5O3
CAS: 137862-53-4
EINECS: 604-045-2

Valsartan (Angiotan or Diovan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure. In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI). 


 

Item

Specification

Result

Test Method

Active Ingredeints

 

 

 

 Assay

98.5%

99.5%

HPLC

Physical Control

 

 

 

Identification

Positive

Conforms

TLC

Appearance

white crystalline powder

Complies

Visual

Odor

Characteristic

Complies

Organoleptic

Taste

Characteristic

Conforms

Organoleptic

Sieve Analysis

100% pass 80 mesh

Complies

80 Mesh Screen

Loss on Drying

5% Max

3.37%

5g/105C /5hrs

Solubility Solubility

in water

Conforms

Visual

Ash

3% Max

2.84%

2g/525C/5hrs

Chemical Control

 

 

 

Sulphate

0.5% Max

Complies

2g/525C/5hrs

Insolubles In Ethanol

10ppm Max

5.3ppm

 

Ethanol Resides

0.2% Max

Complies

 

Arsenic (As)

NMT 2ppm

Conforms

Atomic Absorption

Cadmium(Cd)

NMT 1ppm

Conforms

Atomic Absorption

Lead (Pb)

NMT 2ppm

Conforms

Atomic Absorption

Chlorate (Cl)

NMT 1ppm

Conforms

Atomic Absorption

Phosphate Organics

NMT 1ppm

Conforms

Gas Chromatography

Heavy Metals

20ppm Max

Complies

Atomic Absorption

Pesticides Residues

NMT 1ppm

Conforms

Gas Chromatography



Valsartan is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of hypertension patients who used other antihypertensive drugs without efficacy , is a new generation of highly efficient antihypertensive drugs.

Valsartan (Angiotan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.[1] In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI).[2] In 2005, Angiotan was prescribed more than 12 million times in the United States and global sales were approximately $6.1 billion in 2010.[3] 

Name:

Valsartan
Grade:  Pharmaceutical Grade
MF: C24H29N5O3
CAS: 137862-53-4
EINECS: 604-045-2

Valsartan (Angiotan or Diovan) is an angiotensin II receptor antagonist (more commonly called an "ARB", or angiotensin receptor blocker), with particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure. In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI). 

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