Brand Name: SGONEK
Price: $700 -$900/Kilogram
Place of Origin: Shaanxi, China
Certification: ISO FDA SG COA MSDS
Grade: Medicine Grade
Payment Terms: T/T, Western Union, MoneyGram
| Product Name: | Dexamethasone | Cas No.: | 50-02-02 |
| Molecular Formula: | C22H29FO5 | Purity: | 99%min |
| Brand Name: | SGONEK | Certification: | ISO FDA SG COA MSDS |
| CAS No. | 50-02-02 |
| Model Number | SGONEK-Dexamethasone |
| Appearance | White Powder |
| Purity | 99%min |
| Siez | 100% Pass 80 Mesh |
| Sample | 1-5g free |
| Test Method | HPLC UV |
| Package | 1KG/Bag,5kg/bag,25kg/bag |
| Certificate | ISO/FDA/S G S/MSDS |
| MOQ | 1KG |
| Storage | Cool Dry Place |
Dexamethasone is a type of corticosteroid medication.It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.In adrenocortical insufficiency, it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone.In preterm labor, it may be used to improve outcomes in the baby.It may be taken by mouth, as an injection into a muscle, or intravenously.The effects of dexamethasone are frequently seen within a day and last for about three days.
| Item | Specification | Result |
| Appearance | White powder | Conforms |
| Identification | B:IR | Conforms |
| C:TLC | ||
| Specific optical | +75°~+80° | +77.2° |
| rotation | ||
| Result | Individual impurity≤0.5% | 0.26% |
| substances | Total impurities≤1.0% | 0.45% |
| Loss on drying | ≤0.5% | 0.06% |
| Assay | 97.0%-103.0% | 99.21% |
| Particle size | 90%<30μm | Conforms |
| Conclusion: The above product conforms to the specification of EP6 | ||
Anti-inflammatory
Dexamethasone is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis and bronchospasm.Idiopathic thrombocytopenic purpura, a decrease in numbers of platelets due to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids.
Cancer
People with cancer undergoing chemotherapy are often given dexamethasone to counteract
certain side effects of their antitumor treatments. Dexamethasone can increase the
antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron.The exact mechanism of this interaction is not well-defined, but it has been theorized that this effect may be
due to, among many other causes, inhibition of prostaglandin synthesis, anti-inflammatory
effects, immunosuppressive effects, or a combination of the aforementioned.
Endocrine
Dexamethasone is the treatment for the very rare disorder of glucocorticoid resistance.
In adrenal insufficiency and Addison's disease, dexamethasone is prescribed when the patient does not respond well to prednisone or methylprednisolone.
It can be used in congenital adrenal hyperplasia in older adolescents and adults to suppress ACTH production. It is typically given at night.
Pregnancy
Dexamethasone may be given to women at risk of delivering prematurely to promote
maturation of the fetus' lungs. This has been associated with low birth weight, although
not with increased rates of neonatal death.
High-altitude illnesses
Dexamethasone is used in the treatment of high-altitude cerebral edema (HACE), as well
as high-altitude pulmonary edema (HAPE). It is commonly carried on mountain-climbing
expeditions to help climbers deal with complications of altitude sickness.
Vomiting
Dexamethasone and ondansetron are more effective than ondansetron alone in preventin postoperative nausea and vomiting.
