Brand Name: SGONEK
Price: $200 -$250/Kilogram
Place of Origin: Shaanxi, China
Certification: ISO FDA SG COA MSDS
Grade: All Grade
Payment Terms: T/T, Western Union, MoneyGram
| Product Name: | Sinomenine | Cas No.: | 115-53-7 |
| Molecular Formula: | C19H23NO4 | Purity: | 99%min |
| Brand Name: | SGONEK | Certification: | ISO FDA SG COA MSDS |
| Product Name | Sinomenine |
| CAS No. | 115-53-7 |
| Purity | 98% |
| Appearance | White Powder |
| Molecular Formula | C19H23NO4 |
| EINECS No. | 204-094-6 |
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Description: Sinomenine or Cocculine is an alkaloid found in the root of the climbing plant Sinomenium acutum which is native to Japan and China. It is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.However its analgesic action against other kinds of pain is limited. Sinomenine is a morphinan derivative, related to opioids such as and the non-opioid cough suppressant dextromethorphan. Its anti-rheumatic effects are thought to be primarily mediated via release of histamine,but other effects such as inhibition of prostaglandin, leukotriene and nitric oxide synthesis may also be involved. |
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Analysis Item
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Specification
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Result
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Test Method
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Assay or Ratio
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NLT 1% Eurycomanone
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1.03%
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HPLC
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Organoleptic properties
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|||
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Appearance
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Brownish yellow to light yellow powder
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Conform
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Visual
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Taste/ Odor
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Characteristic
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Conform
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Organoleptic
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Physical properties
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|||
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Identification
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Positive
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Conform
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HPLC
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Sieve analysis
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100% pass 80mesh
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Conform
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Mesh screen or equivalent
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Moisture content
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≤ 5%
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2.01%
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Eur.Ph.7.0 [2.8.17]
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Total ash
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≤ 10%
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8.63%
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Eur.Ph. <2.4.16>
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Bulk density
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40~60 g/100mL
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46g/100mL
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Eur.Ph. <2.9.34>
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Tap density
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60~90g/100mL
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67g/100mL
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Eur.Ph. <2.9.34>
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Chemical control
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|||
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As
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≤ 2ppm
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< 0.1987ppm
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ICP-MS or equivalent
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Pb
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≤ 3ppm
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< 0.1563ppm
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ICP-MS or equivalent
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Cd
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≤ 1ppm
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< 0.0149ppm
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ICP-MS or equivalent
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Hg
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≤ 0.1ppm
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< 0.0337ppm
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ICP-MS or equivalent
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Solvents Residue
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Meet Eur.Ph.7.0 <5.4>
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Conform
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Eur.Ph. <2.4.24>
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Pesticides Residue
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Meet USP Requirements
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Conform
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USP36 <561>
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Microbiology
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|||
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≤ 10000cfu/g
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Conform
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AOAC or equivalent
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Yeasts & Molds
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≤ 1000cfu/g
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Conform
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AOAC or equivalent
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E.Coli
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Negative
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Conform
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AOAC or equivalent
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Salmonella
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Negative
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Conform
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AOAC or equivalent
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1. Sinomenine have a definite analgesic sedative, antitussive local anesthesia, blood pressure, anti-inflammatory effect, as the plants a strong histamine release agent. Animal experiments suggest the shock and organ damage have a protective effect in clinical practice for the treatment of rheumatoid arthritis and neuralgia.
2. Sinomenine is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.However its analgesic action against other kinds of pain is limited. Sinomenine is a morphinan derivative, related to opioids such as and the non-opioid cough suppressant dextromethorphan. Its anti-rheumatic effects are thought to be primarily mediated via release of histamine,but other effects such as inhibition of prostaglandin, leukotriene and nitric oxide synthesis may also be involved.
1.Sinomenine is mainly used in pharmaceutical field to be effective in neuralgia and rheumatic diseases.
2.Sinomenine can be used as health care products,daily necessities and cosmetics and other fields.
