Pharmaceutical Grade Good Price CAS 106685-40-9 99% Adapalen

Brand Name: SGONEK

Price: $5 -$15/Gram

Place of Origin: Shaanxi, China

Certification: ISO FDA SG COA MSDS

Grade: Pharmaceutcial Grade

Payment Terms: T/T, Western Union, MoneyGram

Product Name:  Adapalene Cas No.:  106685-40-9
Molecular Formula:  C28H28O3 Purity:  99%min
Brand Name:  SGONEK Certification:  ISO FDA SG COA MSDS

Pharmaceutical Grade Good Price CAS 106685-40-9 99% Adapalen

 

Product Name  Adapalene Powder
CAS No.  106685-40-9
Purity  99%
Appearance  White Powder
Molecular Formula  C28H28O3
EINECS No.  1308068-626-2

Description: 

Adapalene is a second-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions.

It is effective against acne conditions where comedones are predominant.  

 


 

Test Item
Specifications
Result
Description
   
Appearance
Off white or white white crystalline     powder
white crystalline powder
Identification
By infrared spectrum By HPLC
Conforms
Melting Range
319-322℃
320-322℃
Residual Solvent
DMA≤ 0.109
≤0.01
 
HAc≤0.5%
≤0.01
Partical Size
≤50um
≤50um
Related Substances
Total Impurities:NMT 0.5%
0.003
 
Single Impurity:NMT 0.1%
0.0008
Assay
NLT 99.50%
0.9956
Heavy metals
NMT 20 ppm
Conforms
Loss On Drying
NMT 0.5%
0.0034
Residue on Ignition
NMT 0.1%
0.0007
Chloride
NMT 0.02%
<0.02%
Vitriol
NMT 0.02%
<0.02%
Conclusion: The product conforms to  USP EP JP Etc

 


Adapalene is a retinoid, in vivo and in vitro models of inflammation were demonstrated to have anti-inflammatory properties. Stable chemical structure of adapalene, in the air and light without decomposing. Mechanism and adapalene with formic acid and specific nuclear retinoic acid receptor combined with retinoic acid is the combination of adapalene and protein and binding of cytoplasmic receptors.
In mice to establish animal model of skin drug test proved that adapalene can treat acne, and acne vulgaris and differentiation process as a role. The mechanism of adapalene is considered by the hair follicle epithelium of normal cell differentiation and reduce microcomedo formation.


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