Food additive price beta-cyclodextrin cyclodextrin beta cycl
|
CAS No. |
128446-35-5 |
|
Model Number |
SGONEK-beta cyclodextrin |
|
Purity |
99% |
|
Appearance |
White Powder |
|
Grade |
Pharmaceutcial Grade |
|
Siez |
100% Pass 80 Mesh |
|
Sample |
1-5g free |
|
Test Method |
HPLC UV |
|
Package |
1KG/Bag,5kg/bag,25kg/bag |
|
Certificate |
ISO/FDA/S G S/MSDS |
|
MOQ |
1KG |
|
Storage |
Cool Dry Place |
Cyclodextrin (CD) is a general term for a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase produced by Bacillus, usually containing 6 to 12 D-pyrans Glucose unit. Among them, the most studied and of practical significance are molecules containing 6, 7, and 8 glucose units, which are called alpha-, beta-, and gama-cyclodextrin, respectively (Figure 1). Based on the results of X-ray crystal diffraction, infrared spectroscopy, and nuclear magnetic resonance spectroscopy, it is determined that each D(+)-glucopyranose constituting the cyclodextrin molecule is a chair conformation. Each glucose unit is linked by a 1,4-glycosidic bond to form a ring. Since the glycosidic bond connecting the glucose unit cannot rotate freely, cyclodextrin is not a cylindrical molecule but a slightly conical ring.
|
Item |
Standard |
Inspection Result |
|
Appearance |
White powder |
pass |
|
Molar Substitution |
0.40~1.50 |
pass |
|
Betadex |
≤1.5% |
pass |
|
Propylene Glycol |
≤2.5% |
pass |
|
Any Other Single Impurity |
≤0.25% |
pass |
|
Total Impurities Excluding Betadex and Propylene Glycol |
≤1.0% |
pass |
|
Propylene Oxide |
≤1ppm |
pass |
|
Loss on Drying |
≤10.0% |
pass |
|
Clarity of Solution |
1.0g/2ml water solution is clear and transparent |
pass |
|
Conductivity |
≤200µS/cm |
pass |
|
Bacterial Endotoxins Test |
According to preparation needs |
pass |
|
The total aerobic microbial count |
≤1000cfu/g |
pass |
|
The total combined moulds and yeasts count |
≤100cfu/g |
pass |
|
Purity |
99% |
pass |
1. Pharmaceutical industry
Cyclodextrin can effectively increase the solubility and dissolution rate of some poorly water-soluble drugs in water. For example, prostaglandin-CD inclusion compound can increase the solubility of the main drug to make injections. It can also improve the stability and bioavailability of drugs (such as Changkang granule volatile oil); reduce the bad smell or bitterness of drugs (such as andrographis paniculata); reduce the irritation and toxic side effects of drugs (such as diclofenac sodium); and make drugs (such as diclofenac sodium) Berberine hydrochloride) slow release and improve the dosage form.
2. Food industry
Due to the unique molecular capsule structure of cyclodextrin, it has also been widely exploited and applied in the food field in recent years. It can also act as an emulsifier in foods and beverages that convert liquid foods into foods in a solid state, so that the flavor oil forms an inclusion complex, and is directly used in an aqueous solution to make the food incompatible The ingredients are evenly mixed, which can protect the colorant from sunlight, ultraviolet light, gas, oxidation, thermal shock and other color sounds, greatly prolonging the fading time. In addition, it has significant effects on improving the transmission performance of the composite ingredients of the processing technology in the food system, changing the texture and density of the solid food, and improving the taste of the food.
3. Daily Chemical
The use of cyclodextrins with surfactants in shampoos and kitchen cleaners can reduce the irritation of surfactants on the skin; the use of cyclodextrins can also remove oil stains on fabrics; in the dyeing process, the use of cyclodextrins can Significantly reduce the initial dyeing rate of the dye, improve level dyeing and fiber coloring.
4. Environmental protection
The application of cyclodextrin in environmental protection is based on its ability to form stable inclusions with pollutants, thereby reducing environmental pollution. Its unique molecular structure can be used for biological treatment of industrial wastewater. In addition, the air freshener can slowly release gas molecules by adding cyclodextrin to prolong the duration of fragrance.
5. Agriculture
Pyrethroids are a very important class of insecticides. Cyclodextrin can solve the problem that it is insoluble in water and consumes a lot of organic solvents. It is an effective way to solve the problem that pyrethroids pollute the environment. For fish feed containing unsaturated fatty acids, the fatty acids are encapsulated with cyclodextrin to prevent their diffusion into the water.
Cyclodextrin is widely used in medicine, food, agriculture, cosmetics, and more fields.
